Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13657281 | 1.00 | MAOA (0.32) | MAOAMAOBLMNATSHR | |
| SCHEMBL10938530 | 0.84 | MAPT (0.33) | MAOAMAOB | |
| SCHEMBL10937868 | 0.83 | MAPT (0.33) | MAOAMAOB | |
| SCHEMBL10935590 | 0.83 | MAPT (0.33) | MAOAMAOB | |
| SCHEMBL4865141 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL4560700 | 0.75 | — | — | |
| SCHEMBL5744965 | 0.73 | — | — | |
| SCHEMBL30130599 | 0.72 | LMNA (0.30) | LMNATSHR | |
| SCHEMBL20969186 | 0.70 | — | — | |
| SCHEMBL15661939 | 0.69 | MAPT (0.34) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5461156-A | Stereocontrolled synthesis of cis-bicyclic compounds | ELI LILLY AND COMPANY (US) | 1995-10-24 | — | — | US | disclosed |