Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280014 | 1.00 | ALDH1A1 (0.65) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL9275456 | 0.89 | POLB (0.62) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL9275466 | 0.89 | POLB (0.62) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL9275791 | 0.87 | F2 (0.71) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL9275807 | 0.87 | F2 (0.71) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL11428375 | 0.86 | ALDH1A1 (0.61) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL9280775 | 0.85 | FKBP1A (0.72) | POLBFKBP1A | |
| SCHEMBL9280780 | 0.85 | FKBP1A (0.72) | POLBFKBP1A | |
| SCHEMBL9280850 | 0.85 | KMT2A (0.58) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL9280876 | 0.85 | KMT2A (0.58) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9193762-B2 | Selective inhibitors of prolylcarboxypeptidase | UNIVERSITY OF MISSISSIPPI (US) | 2015-11-24 | — | — | US | disclosed |
| US-20130310311-A1 | NOVEL SELECTIVE INHIBITORS OF PROLYLCARBOXYPEPTIDASE | THE UNIVERSITY OF MISSISSIPPI | 2013-11-21 | — | — | US | disclosed |
| WO-2012075287-A2 | NOVEL SELECTIVE INHIBITORS OF PROLYLCARBOXYPEPTIDASE | THE UNIVERSITY OF MISSISSIPPI (US) | 2012-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310311-A1 | NOVEL SELECTIVE INHIBITORS OF PROLYLCARBOXYPEPTIDASE | PREP, PEPD, DPEP1 | ALDH1A1 859/4885CYP3A4 1353/4885CYP2C9 1078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.