Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1833547 | 0.80 | PARP1 (0.50) | PARP1KCNH2SLC6A2SLC6A4HTR2A | |
| SCHEMBL17875570 | 0.79 | PARP1 (0.41) | PARP1KCNH2SLC6A2SLC6A4HTR2A | |
| SCHEMBL17875578 | 0.78 | HRH1 (0.37) | PARP1 | |
| SCHEMBL17876422 | 0.77 | PARP1 (0.47) | PARP1KCNH2SLC6A2SLC6A4NR3C1 | |
| SCHEMBL16324834 | 0.77 | PARP1 (0.47) | PARP1KCNH2SLC6A2SLC6A4NR3C1 | |
| SCHEMBL17875582 | 0.76 | PARP1 (0.39) | PARP1KCNH2SLC6A2SLC6A4NR3C1 | |
| SCHEMBL17875580 | 0.74 | PARP1 (0.37) | PARP1KCNH2SLC6A2SLC6A4CCR8 | |
| SCHEMBL18559464 | 0.72 | PARP1 (0.44) | PARP1KCNH2SLC6A2SLC6A4NR3C1 | |
| SCHEMBL16361857 | 0.72 | PARP1 (0.44) | PARP1KCNH2SLC6A2SLC6A4NR3C1 | |
| SCHEMBL16362041 | 0.72 | DRD1 (0.49) | PARP1KCNH2SLC6A2SLC6A4DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150025280-A1 | LIGANDS FOR RHODIUM CATALYZED REDUCTIVE CARBONYLATION OF ALCOHOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-01-22 | — | — | US | disclosed |
| US-20150025280-A1 | LIGANDS FOR RHODIUM CATALYZED REDUCTIVE CARBONYLATION OF ALCOHOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-01-22 | — | — | US | disclosed |
| WO-2013096631-A1 | LIGANDS FOR RHODIUM CATALYZED REDUCTIVE CARBONYLATION OF ALCOHOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-27 | — | — | WO | disclosed |
| US-5434117-A | Catalyst system and copolymerization process | SHELL OIL COMPANY (US) | 1995-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025280-A1 | LIGANDS FOR RHODIUM CATALYZED REDUCTIVE CARBONYLATION OF ALCOHOLS | ADH5, ADH1C, ADH1A | PARP1 1844/4885KCNH2 1476/4885SLC6A2 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.