SCHEMBL9280592

SCHEMBL9280592

C=CCc1cc(Br)c([N+](=O)[O-])cc1[N+](=O)[O-]

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 1/20 0.38
ALDH1A1 P00352 4/20 0.37
MAPT P10636 3/20 0.37
SNCA P37840 1/20 0.37
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
CYP3A4 P08684 1/20 0.36
PKM P14618 1/20 0.36
MAPK1 P28482 1/20 0.35
CYP2D6 P10635 1/20 0.34
KDM4E B2RXH2 1/20 0.33
XDH P47989 1/20 0.33
POLB P06746 2/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
CTSB P07858 1/20 0.33
ERN1 O75460 1/20 0.33
CYP1A2 P05177 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9282606 0.79 TSHR (0.42) HCAR3ALDH1A1SNCAGABRA1GABRB2
SCHEMBL9001712 0.79 MEN1 (0.48) HCAR3ALDH1A1MAPTSNCAGABRA1
SCHEMBL9001711 0.79 SNCA (0.53) HCAR3ALDH1A1MAPTSNCAGABRA1
SCHEMBL13213567 0.78 S100A4 (0.42) HCAR3ALDH1A1MAPTSNCAGABRA1
SCHEMBL7645214 0.77 GABRA1 (0.41) HCAR3ALDH1A1MAPTSNCAGABRA1
SCHEMBL3179870 0.74 ALDH1A1 (0.50) ALDH1A1MAPTCYP3A4PKMMAPK1
SCHEMBL11819621 0.74 POLB (0.39) HCAR3ALDH1A1MAPTSNCAGABRA1
SCHEMBL7080582 0.72 CYP1A2 (0.57) ALDH1A1MAPTCYP3A4MAPK1CYP2D6
SCHEMBL30496244 0.72 CYP1A2 (0.57) ALDH1A1MAPTCYP3A4MAPK1CYP2D6
SCHEMBL11077537 0.72 MAPT (0.45) ALDH1A1MAPTGABRA1GABRB2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5382702-A Process for the production of 5-alkoxy-2,4-dinitro-alkylbenzenes WELLA AKTIENGESELLSCHAFT (DE) 1995-01-17 US disclosed