SCHEMBL9280741

SCHEMBL9280741

C=CC[Si](CC=C)(C1=CC=CC1)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.36
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
ADRA1B P35368 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31530506 0.85 PNMT (0.45) PNMTDRD2DRD4DRD3NPC1
SCHEMBL60587 0.78 PNMT (0.39) PNMTDRD2DRD4DRD3NPC1
SCHEMBL29138460 0.78 PNMT (0.36) PNMTDRD2DRD4DRD3NPC1
SCHEMBL31530499 0.77 PNMT (0.43) PNMTDRD2DRD4DRD3NPC1
SCHEMBL6672325 0.77 PNMT (0.38) PNMTDRD2DRD4DRD3NPC1
SCHEMBL6678467 0.76 PNMT (0.37) PNMTDRD2DRD4DRD3NPC1
SCHEMBL6676042 0.75 PNMT (0.36) PNMTDRD2DRD4DRD3NPC1
SCHEMBL6675588 0.75 PNMT (0.37) PNMTDRD2DRD4DRD3NPC1
SCHEMBL6675606 0.74 PNMT (0.35) PNMTDRD2DRD4DRD3NPC1
SCHEMBL6677716 0.74 PNMT (0.35) PNMTDRD2DRD4DRD3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7138275-A None JP disclosed
JP-H07138275-A METALLOCENE, AND OLEFIN POLYMERIZATION USING THE SAME AS CATALYST PHILLIPS PETROLEUM CO 1995-05-30 JP disclosed