SCHEMBL60587

SCHEMBL60587

C[Si](C)(C1=CC=CC1)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33
PGR P06401 1/20 0.32
KDR P35968 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6678467 0.86 PNMT (0.37) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6672325 0.84 PNMT (0.38) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6677716 0.84 PNMT (0.35) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6675606 0.84 PNMT (0.35) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL61027 0.83 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL29843943 0.83 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6676042 0.82 PNMT (0.36) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL29138460 0.82 PNMT (0.36) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6675588 0.79 PNMT (0.37) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL7052932 0.79 PNMT (0.38) PNMTNPC1RAB9ADRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590174-B2 Curable compositions comprising telechelic polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2026-03-31 US disclosed
EP-3902808-B1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-14 EP disclosed
EP-3902810-B1 CURABLE COMPOSITIONS COMPRISING TELECHELIC POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-14 EP disclosed
EP-3356374-B1 MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2025-09-24 EP disclosed
EP-3902807-B1 ORGANOMETALLIC CHAIN TRANSFER AGENTS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-09 EP disclosed
US-12351707-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-08 US disclosed
US-12275810-B2 Telechelic polyolefins and processes for preparing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2025-04-15 US disclosed
US-12180314-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2024-12-31 US disclosed
US-12129368-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2024-10-29 US disclosed
EP-4435013-A2 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING Dow Global Technologies LLC (US) 2024-09-25 EP disclosed
EP-0963990-A1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-15 EP disclosed
WO-1999048605-A1 ION EXCHANGED ALUMINIUM-MAGNESIUM OR FLUORINATED MAGNESIUM SILICATE AEROGELS AND CATALYST SUPPORTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1999-09-30 WO disclosed
WO-1999042467-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 1999-08-26 WO disclosed
WO-1999041289-A1 IMPROVED OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1999-08-19 WO disclosed
WO-1999006449-A1 ZWITTERIONIC CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1999-02-11 WO disclosed
WO-1999006413-A1 CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1999-02-11 WO disclosed
WO-1999006412-A1 PERFLUORONAPHTHYL SUBSTITUTED BORON CONTAINING CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1999-02-11 WO disclosed
EP-0617044-B1 Process for preparing cyclopentadienyl group-containing silicon compound or cyclopentadienyl group-containing germanium compound MITSUI CHEMICALS INC (JP) 1999-01-20 EP disclosed
US-5360921-A REACTING LITHIUM, SODIUM OR POTASSIUM SALT OF A CYCLOPENTADIENE DERIVATIVE WITH A SILICON OR GERMANIUM HALIDE COMPOUND IN THE PRESENCE OF A CYANIDE OR A THIOCYANATE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-11-01 US disclosed
EP-0617044-A2 Process for preparing cyclopentadienyl group-containing silicon compound or cyclopentadienyl group-containing germanium compound MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12129368-B2 Curable compositions comprising unsaturated polyolefins ACSL6, ELOVL6, ALOX5 PNMT 3858/4885NPC1 1682/4885RAB9A 4806/4885
US-12590174-B2 Curable compositions comprising telechelic polyolefins CCT2, TCP1, ECH1 PNMT 1496/4885NPC1 3703/4885RAB9A 4811/4885
US-12351707-B2 Curable compositions comprising unsaturated polyolefins ACSL6, ELOVL6, ALOX5 PNMT 3858/4885NPC1 1682/4885RAB9A 4806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.