SCHEMBL29138460

SCHEMBL29138460

CO[Si](OC)(C1=CC=CC1)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
HIF1A Q16665 3/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HTR7 P34969 1/20 0.31
HTR2B P41595 1/20 0.31
KDR P35968 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1906185 0.84 PNMT (0.45) PNMTNPC1RAB9AHIF1ADRD2
SCHEMBL60587 0.82 PNMT (0.39) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6678467 0.80 PNMT (0.37) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6676042 0.79 PNMT (0.36) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6675606 0.78 PNMT (0.35) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6672325 0.78 PNMT (0.38) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6677716 0.78 PNMT (0.35) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL9280741 0.78 PNMT (0.36) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6675588 0.76 PNMT (0.37) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL1985427 0.75 PNMT (0.45) PNMTNPC1RAB9AHIF1ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118974105-A Olefin polymerization catalyst comprising magnesium, titanium, epoxy compounds and internal electron donors such as compounds based on 1, 2-phenylene dibenzoate 格雷斯公司 2024-11-15 CN disclosed
CN-117355546-A Spherical catalyst component for olefin polymerization 格雷斯公司 2024-01-05 CN disclosed