Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926338 | 0.91 | FKBP1A (0.49) | MEN1KMT2AFKBP1A | |
| SCHEMBL926724 | 0.91 | PSEN1 (0.46) | TP53RORCFKBP1A | |
| SCHEMBL927067 | 0.91 | KMT2A (0.47) | MAPTKMT2ARORCFKBP1A | |
| SCHEMBL927595 | 0.90 | POLB (0.51) | MEN1KMT2ALMNAFKBP1APOLB | |
| SCHEMBL927527 | 0.90 | FKBP1A (0.48) | MEN1KMT2ALMNARORCFKBP1A | |
| SCHEMBL927224 | 0.90 | NAMPT (0.44) | MEN1KMT2ARORCFKBP1A | |
| SCHEMBL926214 | 0.90 | TGM2 (0.42) | MEN1KMT2ALMNARORCFKBP1A | |
| SCHEMBL926670 | 0.87 | BDKRB1 (0.44) | RORCFKBP1A | |
| SCHEMBL926912 | 0.87 | FKBP1A (0.54) | MEN1KMT2ALMNARORCFKBP1A | |
| SCHEMBL926686 | 0.87 | ESRRG (0.47) | MEN1KMT2ARORCFKBP1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872021-B2 | LXR receptor modulators | LABORATORIES FOURNIER S.A. (FR) | 2011-01-18 | — | — | US | disclosed |
| US-20070099960-A1 | LXR receptor modulators | LABORATOIRES FOURNIER S.A. (FR) | 2007-05-03 | — | — | US | disclosed |
| EP-1742918-A1 | LXR RECEPTOR MODULATORS | LABORATOIRES FOURNIER S.A. (FR) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005121093-A1 | LXR RECEPTOR MODULATORS | LABORATOIRES FOURNIER S.A. (FR) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099960-A1 | LXR receptor modulators | NR1H2, NR1H3, PPARD | MAPT 1687/4885MEN1 4595/4885KMT2A 2387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.