Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL927527 | 0.96 | FKBP1A (0.48) | POLBKMT2AMEN1LMNAFKBP1A | |
| SCHEMBL926338 | 0.94 | FKBP1A (0.49) | KMT2AMEN1FKBP1AALDH1A1MAPK1 | |
| SCHEMBL926686 | 0.93 | ESRRG (0.47) | POLBKMT2AMEN1FKBP1AALDH1A1 | |
| SCHEMBL926912 | 0.93 | FKBP1A (0.54) | POLBKMT2AMEN1LMNAFKBP1A | |
| SCHEMBL928733 | 0.92 | PSEN1 (0.51) | POLBKMT2AMEN1FKBP1AALDH1A1 | |
| SCHEMBL926834 | 0.92 | RORC (0.50) | POLBFKBP1AALDH1A1CA1CA2 | |
| SCHEMBL926406 | 0.92 | FKBP1A (0.47) | POLBKMT2AMEN1FKBP1AALDH1A1 | |
| SCHEMBL929397 | 0.92 | ESRRG (0.47) | POLBKMT2AMEN1LMNAFKBP1A | |
| SCHEMBL928076 | 0.90 | MAPT (0.43) | POLBKMT2AMEN1LMNAFKBP1A | |
| SCHEMBL926214 | 0.90 | TGM2 (0.42) | POLBKMT2AMEN1LMNAFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872021-B2 | LXR receptor modulators | LABORATORIES FOURNIER S.A. (FR) | 2011-01-18 | — | — | US | disclosed |
| US-20070099960-A1 | LXR receptor modulators | LABORATOIRES FOURNIER S.A. (FR) | 2007-05-03 | — | — | US | disclosed |
| EP-1742918-A1 | LXR RECEPTOR MODULATORS | LABORATOIRES FOURNIER S.A. (FR) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005121093-A1 | LXR RECEPTOR MODULATORS | LABORATOIRES FOURNIER S.A. (FR) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099960-A1 | LXR receptor modulators | NR1H2, NR1H3, PPARD | POLB 3286/4885KMT2A 2387/4885MEN1 4595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.