⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2383228 | 0.57 | MAPT (0.60) | — | |
| SCHEMBL3637470 | 0.57 | CYP3A4 (0.47) | — | |
| SCHEMBL4553774 | 0.56 | KDM4E (0.56) | — | |
| SCHEMBL13011189 | 0.55 | ALDH1A1 (0.36) | — | |
| SCHEMBL28153565 | 0.54 | POLB (0.36) | — | |
| SCHEMBL372547 | 0.54 | — | — | |
| Hydrochloric Acid SCHEMBL20447769 | 0.53 | ALOX15 (0.42) | — | |
| SCHEMBL22441532 | 0.53 | — | — | |
| Hydrochloric Acid SCHEMBL741807 | 0.53 | ALOX15 (0.42) | — | |
| SCHEMBL7386383 | 0.52 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735869-A1 | A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS | NOVO NORDISK A/S (DK) | 1996-10-09 | — | — | EP | disclosed |
| EP-0714394-A1 | ANTIPSYCHOTIC METHOD | NOVO NORDISK A/S (DK) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995017180-A1 | A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS | NOVO NORDISK A/S (DK) | 1995-06-29 | — | — | WO | disclosed |
| WO-1995005379-A1 | ANTIPSYCHOTIC METHOD | NOVO NORDISK A/S (DK) | 1995-02-23 | — | — | WO | disclosed |