SCHEMBL9280957

SCHEMBL9280957

CC(C)(C)c1cc(C(=O)Oc2cccc3ccccc23)cc(C(C)(C)C)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.55
PTGES O14684 1/20 0.55
KMT2A Q03164 5/20 0.48
HSD17B10 Q99714 4/20 0.48
GAA P10253 3/20 0.48
ALDH1A1 P00352 3/20 0.48
PTGS1 P23219 2/20 0.48
PGR P06401 1/20 0.48
MAPK1 P28482 1/20 0.48
SERPINE1 P05121 1/20 0.48
ESR1 P03372 4/20 0.47
ESR2 Q92731 4/20 0.47
MEN1 O00255 3/20 0.47
MAPT P10636 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 1/20 0.47
JAK2 O60674 1/20 0.47
USP2 O75604 1/20 0.47
ALOX15 P16050 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2374902 0.84 SERPINE1 (0.54) ALOX5GAAALDH1A1PTGS1SERPINE1
SCHEMBL27059849 0.82 ALOX5 (0.70) ALOX5PTGESKMT2AHSD17B10GAA
SCHEMBL1796301 0.81 PTGS1 (0.48) ALOX5KMT2APTGS1SERPINE1ESR1
SCHEMBL8777982 0.81 TSHR (0.58) ALOX5GAAPTGS1SERPINE1SMN1; SMN2
SCHEMBL29612711 0.81 PTGS1 (0.48) ALOX5KMT2APTGS1SERPINE1ESR1
SCHEMBL11786628 0.78 SELL (0.52) ALOX5KMT2AGAAPTGS1MAPK1
SCHEMBL9807328 0.78 SERPINE1 (0.48) ALOX5KMT2AHSD17B10GAAPTGS1
SCHEMBL5081762 0.78 ALOX5 (0.71) ALOX5PTGESKMT2AHSD17B10GAA
SCHEMBL29613809 0.78 ALOX5 (0.71) ALOX5PTGESKMT2AHSD17B10GAA
SCHEMBL1043660 0.77 ALOX5 (0.63) ALOX5PTGESKMT2AHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7112955-A None JP disclosed
JP-H07112955-A 4-HYDROXYBENZOIC ACID ESTER AND ITS USE SUMITOMO CHEM CO LTD 1995-05-02 JP disclosed
US-4233208-A OXIDATION RESISTANCE, RADIATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1980-11-11 US disclosed
US-4207229-A STABILIZING POLYPROPYLENE AGAINST THERNAL, OXIDATIVE AND ULTRAVIOLET LIGHT DEGRADATION CIBA-GEIGY CORPORATION (US) 1980-06-10 US disclosed
US-4195016-A STABILIZERS OF POLYMERS AGAINST THERMAL, OXIDATIVE, AND ULTRAVIOLET LIGHT DEGRADATION CIBA-GEIGY CORPORATION (US) 1980-03-25 US disclosed
US-4182704-A STABILIZERS CIBA-GEIGY CORPORATION (US) 1980-01-08 US disclosed
US-4180497-A STABILIZERS FOR ORGANIC POLYMERS AGAINST THERMAL, OXIDATIVE AND UV LIGHT DEGRADATION CIBA-GEIGY CORPORATION (US) 1979-12-25 US disclosed
US-4180498-A STABILIZERS OF POLYMERS AGAINST THERMAL, OXIDATIVE, AND ULTRAVIOLET LIGHT DEGRADATION CIBA-GEIGY CORPORATION (US) 1979-12-25 US disclosed
US-4094855-A Hindered phenyl phosphites CIBA-GEIGY CORPORATION (US) 1978-06-13 US disclosed