Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8468117 | 0.98 | RXRA (0.31) | RXRAGRIN1GRIN2B | |
| SCHEMBL2185795 | 0.77 | RXRA (0.32) | RXRAGRIN1GRIN2B | |
| SCHEMBL27603391 | 0.75 | RXRA (0.38) | RXRAGRIN1GRIN2BHDAC8 | |
| SCHEMBL5378152 | 0.75 | KDM4E (0.38) | RXRAGRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL5573936 | 0.74 | KDM4E (0.37) | RXRAGRIN1GRIN2B | |
| SCHEMBL9194404 | 0.71 | HDAC8 (0.33) | RXRAGRIN1GRIN2BHDAC8 | |
| SCHEMBL5582737 | 0.71 | S1PR4 (0.41) | — | |
| SCHEMBL2186121 | 0.70 | RXRA (0.40) | RXRAGRIN1GRIN2B | |
| SCHEMBL6514150 | 0.67 | — | — | |
| SCHEMBL6826431 | 0.67 | MEN1 (0.41) | RXRAGRIN1GRIN2BHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660827-A1 | HETEROCYCLIC COMPOUNDS WIHT PARASITICAL ACTIVITY. | ZENECA LTD (GB) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006777-A1 | HETEROCYCLIC COMPOUNDS WIHT PARASITICAL ACTIVITY | ZENECA LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |