Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8468120 | 0.98 | MEN1 (0.40) | MEN1KMT2AL3MBTL1LMNATSHR | |
| SCHEMBL31729647 | 0.84 | MEN1 (0.40) | MEN1KMT2AL3MBTL1LMNATSHR | |
| SCHEMBL1555445 | 0.78 | MEN1 (0.39) | MEN1KMT2AL3MBTL1LMNATSHR | |
| SCHEMBL26654252 | 0.78 | DGAT1 (0.41) | MEN1KMT2AL3MBTL1LMNATSHR | |
| SCHEMBL28011844 | 0.78 | CFTR (0.47) | MEN1KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL3698077 | 0.78 | HDAC1 (0.32) | MEN1KMT2AL3MBTL1LMNATDP1 | |
| SCHEMBL17114828 | 0.76 | MEN1 (0.38) | MEN1KMT2AL3MBTL1LMNATSHR | |
| SCHEMBL28867958 | 0.76 | MEN1 (0.57) | MEN1KMT2AL3MBTL1LMNATSHR | |
| SCHEMBL14375560 | 0.75 | NUDT1 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2RXRA | |
| SCHEMBL25164045 | 0.75 | RXRA (0.40) | MEN1KMT2AL3MBTL1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246932-A1 | ARYL 3-OXOPIPERAZINE CARBOXAMIDES AND HETEROARYL 3-OXOPIPERAZINE CARBOXAMIDES AS NAV1.8 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-07-25 | — | — | US | claimed |
| US-12473289-B2 | Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use | AMGEN INC. (US) | 2025-11-18 | — | — | US | disclosed |
| EP-4522599-A1 | METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS | EDGEWISE THERAPEUTICS, INC. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220180-A1 | METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS | EDGEWISE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| EP-4149466-A1 | SUBSTITUTED PYRIDAZINONE FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES | EDGEWISE THERAPEUTICS, INC. (US) | 2023-03-22 | — | — | EP | disclosed |
| US-11312706-B2 | Cyclohexyl acid pyrazole azines as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-04-26 | — | — | US | disclosed |
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-107001259-A | Substituted azetidine derivatives as TAAR ligands | 豪夫迈·罗氏有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-106661043-A | 2-oxa-5-azabicyclo[2.2.1]heptan-3-yl derivatives | 豪夫迈·罗氏有限公司 | 2017-05-10 | — | — | CN | disclosed |
| WO-2004111000-A2 | PIPERIDYL DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2004-12-23 | — | — | WO | disclosed |
| EP-0660827-A1 | HETEROCYCLIC COMPOUNDS WIHT PARASITICAL ACTIVITY. | ZENECA LTD (GB) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006777-A1 | HETEROCYCLIC COMPOUNDS WIHT PARASITICAL ACTIVITY | ZENECA LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |
| US-4704159-A | PRE- AND POSTERMERGENCE IN CORN | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-03 | — | — | US | disclosed |
| US-4609398-A | PRE- AND POSTEMERGENT CONTROL OF WEEDS IN CORN | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246932-A1 | ARYL 3-OXOPIPERAZINE CARBOXAMIDES AND HETEROARYL 3-OXOPIPERAZINE CARBOXAMIDES AS NAV1.8 INHIBITORS | TRPV1, SCN8A, SCN2A | MEN1 4489/4885KMT2A 1754/4885L3MBTL1 4098/4885 |
| US-12473289-B2 | Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use | SCD5, SCD, FADS2 | MEN1 3962/4885KMT2A 3001/4885L3MBTL1 2792/4885 |
| US-11312706-B2 | Cyclohexyl acid pyrazole azines as LPA antagonists | LPAR3, LPAR1, LPAR2 | MEN1 3193/4885KMT2A 2889/4885L3MBTL1 4374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.