Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9403954 | 0.87 | SLC6A2 (0.47) | KEAP1SLC5A2SLC5A1SLC6A4SLC6A2 | |
| SCHEMBL2140027 | 0.83 | HTR2A (0.54) | SLC6A4SLC6A2SLC6A3POLBHTR2A | |
| SCHEMBL6666921 | 0.83 | TSHR (0.56) | KEAP1HTR2ATSHRCYP3A4IDO1 | |
| SCHEMBL12270341 | 0.82 | KCNH2 (0.51) | KCNH2AGXTPOLBCARM1PRMT1 | |
| SCHEMBL9232175 | 0.81 | LTA4H (0.60) | AGXTSLC5A2SLC5A1IDO1 | |
| SCHEMBL9283180 | 0.79 | IDO1 (0.50) | TSHRCYP3A4CYP2D6CYP2C19IDO1 | |
| SCHEMBL9231367 | 0.79 | TAAR1 (0.43) | TSHR | |
| SCHEMBL6547993 | 0.79 | POLB (0.45) | KCNH2KEAP1SLC5A2SLC6A4SLC6A2 | |
| SCHEMBL6378299 | 0.79 | POLB (0.51) | KEAP1SLC5A2POLBTSHRCYP3A4 | |
| SCHEMBL605027 | 0.78 | HTR2A (0.48) | KEAP1AGXTSLC5A2SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664316-A1 | Polycarbonate composition having improved resistance to gamma-ray radiation | TEIJIN LIMITED (JP) | 1995-07-26 | — | — | EP | disclosed |