Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896191 | 0.88 | L3MBTL1 (0.46) | L3MBTL1KMT2APOLBCYP1A2MGAM | |
| SCHEMBL11625761 | 0.88 | L3MBTL1 (0.46) | L3MBTL1KMT2APOLBCYP1A2MGAM | |
| SCHEMBL23130411 | 0.83 | L3MBTL1 (0.39) | L3MBTL1KMT2APOLBCYP1A2MGAM | |
| SCHEMBL28741373 | 0.80 | CYP3A4 (0.30) | TSHRLMNACYP3A4HIF1AHSD17B10 | |
| SCHEMBL2947636 | 0.79 | MEN1 (0.34) | KMT2AGAATSHRLMNACYP3A4 | |
| SCHEMBL30605957 | 0.78 | GABRP (0.38) | L3MBTL1KMT2APOLBCYP1A2ALDH1A1 | |
| SCHEMBL6101629 | 0.76 | CHRM1 (0.44) | TSHRLMNACYP3A4HIF1AHSD17B10 | |
| SCHEMBL1603824 | 0.76 | LMNA (0.53) | CYP1A2TSHRLMNACYP3A4HIF1A | |
| SCHEMBL6204910 | 0.76 | LMNA (0.53) | CYP1A2TSHRLMNACYP3A4HIF1A | |
| SCHEMBL11155839 | 0.75 | CYP3A4 (0.35) | TSHRLMNACYP3A4HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728018-A1 | THERAPY | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013095-A2 | THERAPY | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |