Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 3/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | FRK | P42685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949576 | 0.76 | GSK3B (0.49) | CSNK1A1CSNK1DCLK2CSNK1G1MAPK14 | |
| SCHEMBL9196324 | 0.70 | MAPK11 (0.69) | BRAFCSNK1A1CSNK1DMAPK14MAPK13 | |
| SCHEMBL14053450 | 0.68 | KIF11 (0.44) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL15556424 | 0.67 | CSNK2A1 (0.44) | ESR1ESR2 | |
| SCHEMBL7372784 | 0.67 | MAPK14 (0.65) | CSNK1DMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL19868944 | 0.67 | MAPK14 (0.62) | BRAFCSNK1A1CSNK1DMAPK14MAPK13 | |
| SCHEMBL20470626 | 0.66 | MAPT (0.41) | — | |
| SCHEMBL7686704 | 0.65 | CSNK1A1 (0.78) | CSNK1A1CSNK1DCLK2CSNK1G1MAPK14 | |
| SCHEMBL5464157 | 0.65 | KIF11 (0.53) | BRAFMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL19868943 | 0.65 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |