Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 15/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.35 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700768 | 0.88 | FFAR1 (0.53) | FFAR1CHRM2S1PR1FPR1FPR3 | |
| SCHEMBL8876609 | 0.87 | CYP3A4 (0.41) | CYP4F2CYP4A11FFAR1FFAR4FDFT1 | |
| SCHEMBL9180592 | 0.84 | RARA (0.46) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865668 | 0.81 | CYP3A4 (0.36) | CYP4F2CYP4A11CYP3A4RARARARB | |
| SCHEMBL8875500 | 0.81 | CYP3A4 (0.40) | CYP4F2CYP4A11FFAR1FFAR4CYP4Z1 | |
| SCHEMBL9176529 | 0.80 | RARA (0.44) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL9284407 | 0.80 | RARA (0.35) | CYP4F2CYP4A11FFAR1CYP3A4RARA | |
| SCHEMBL8865478 | 0.79 | CYP4F2 (0.34) | CYP4F2CYP4A11FFAR1RARARARB | |
| SCHEMBL8875274 | 0.79 | CYP3A4 (0.41) | CYP4F2CYP4A11FFAR1FFAR4FDFT1 | |
| SCHEMBL8865711 | 0.79 | RARA (0.38) | CYP3A4RARARARBRARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419131-B1 | Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity | ALLERGAN INC (US) | 1995-07-05 | — | — | EP | disclosed |
| US-5278318-A | Acetylation under Friedel Crafts condition | ALLERGAN, INC. (US) | 1994-01-11 | — | — | US | disclosed |
| US-4980369-A | ANTIARTHRITIC AGENTS, SKIN DISORDERS, ANTIULCER AGENTS, WOUND HEALING AGENTS | ALLERGAN, INC. (US) | 1990-12-25 | — | — | US | disclosed |