Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18759662 | 0.98 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1MMP8PKM | |
| SCHEMBL16048 | 0.98 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1MMP8PKM | |
| SCHEMBL19278938 | 0.96 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1MMP8PKM | |
| SCHEMBL8171534 | 0.87 | PIN1 (0.39) | CYP4F2CYP4A11ALDH1A1MMP8KDM4E | |
| SCHEMBL651926 | 0.86 | FDPS (0.44) | CYP4F2CYP4A11ALDH1A1MMP8PKM | |
| Tetrahydrofuran SCHEMBL10517718 | 0.84 | TSHR (0.38) | CYP4F2CYP4A11ALDH1A1MMP8PKM | |
| SCHEMBL9064918 | 0.83 | MMP8 (0.50) | CYP4F2CYP4A11ALDH1A1MMP8PKM | |
| SCHEMBL2237636 | 0.83 | FDPS (0.43) | CYP4F2CYP4A11PKMMEN1KMT2A | |
| SCHEMBL6851372 | 0.82 | MEN1 (0.45) | CYP4F2CYP4A11ALDH1A1MMP8PKM | |
| SCHEMBL2392569 | 0.82 | CYP4F2 (0.33) | CYP4F2CYP4A11ALDH1A1MMP8PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022024-A1 | ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2010123599-A9 | ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-02-17 | — | — | WO | disclosed |
| WO-2010123599-A2 | ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-10-28 | — | — | WO | disclosed |
| EP-0206206-B1 | ERGOLINE DERIVATIVES, PROCESS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION AND USE | FARMITALIA CARLO ERBA S.r.l. (IT) | 1989-09-20 | — | — | EP | disclosed |
| US-4746666-A | Ergoline compounds useful as antiparkinson agents | FARMITALIA CARLO ERBA S.P.A. (IT) | 1988-05-24 | — | — | US | disclosed |
| EP-0206206-A1 | Ergoline derivatives, process for preparing them, pharmaceutical composition and use | FARMITALIA CARLO ERBA S.r.l. (IT) | 1986-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022024-A1 | ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS | CUTA, MMP8, CLPP | CYP4F2 4805/4885CYP4A11 4870/4885ALDH1A1 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.