Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952084 | 0.85 | HTT (0.46) | HTTSMN1; SMN2PKMADAMTS5ALOX15 | |
| SCHEMBL8952116 | 0.78 | NR3C1 (0.45) | HTTSMN1; SMN2ADAMTS5POLBMAPT | |
| SCHEMBL8952208 | 0.73 | HPGD (0.47) | SMN1; SMN2MAPTALDH1A1PTGDR2NR3C1 | |
| SCHEMBL9267572 | 0.73 | PTGS2 (0.47) | PTGS1PTGS2SMN1; SMN2POLBMAPT | |
| SCHEMBL1765721 | 0.73 | PDE4D (0.42) | HTTTSHRALDH1A1NPSR1LMNA | |
| SCHEMBL12361500 | 0.71 | ALDH1A1 (0.56) | HTTPTGS1SMN1; SMN2PKMPOLB | |
| SCHEMBL8952130 | 0.70 | ALDH1A1 (0.39) | HTTADAMTS5POLBALDH1A1NR3C1 | |
| SCHEMBL14747809 | 0.69 | PTGS2 (0.71) | PTGS1PTGS2POLBCYP1A2CYP2C9 | |
| SCHEMBL16989247 | 0.69 | HPGD (0.49) | HTTPTGS1PTGS2SMN1; SMN2POLB | |
| SCHEMBL31672711 | 0.68 | KMT2A (0.38) | PTGS1PTGS2SMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7206825-A | — | — | None | — | — | JP | disclosed |
| JP-H07206825-A | PYRAZOLEGLYCOLIC ACID AMIDE DERIVATIVE | NISSAN CHEM IND LTD | 1995-08-08 | — | — | JP | disclosed |