Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265671 | 0.83 | OXER1 (0.54) | PLA2G2A | |
| SCHEMBL9270261 | 0.83 | OXER1 (0.54) | PLA2G2A | |
| SCHEMBL9265228 | 0.82 | PLA2G2A (0.52) | ALDH1A1HTTPLA2G2A | |
| SCHEMBL9271951 | 0.82 | CNR2 (0.55) | PLA2G2A | |
| SCHEMBL9282528 | 0.81 | GABRA1 (0.44) | PLA2G2A | |
| SCHEMBL7213227 | 0.80 | PLA2G2A (0.43) | PLA2G2A | |
| SCHEMBL7211881 | 0.79 | PSEN1 (0.54) | PLA2G2A | |
| SCHEMBL7206888 | 0.78 | PLA2G2A (0.40) | PLA2G2A | |
| SCHEMBL9263602 | 0.76 | PLA2G2A (0.58) | PLA2G2A | |
| SCHEMBL9264177 | 0.76 | PLA2G2A (0.58) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995013266-A1 | ACYLPYRROLE-ALKANOIC ACIDS AND INDOLE-2-ALKANOIC ACIDS PLUS THEIR DERIVATIVES FOR USE AS INHIBITORS OF PHOSPHOLIPASE A¿2? | MERCKLE GMBH CHEM.-PHARM. FABRIK (DE) | 1995-05-18 | — | — | WO | disclosed |