Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505468 | 0.88 | KMT2A (0.76) | KDRKMT2AMEN1KDM4ETSHR | |
| SCHEMBL6254143 | 0.77 | KDR (1.00) | KDRKMT2AMEN1KDM4ETSHR | |
| SCHEMBL2616458 | 0.76 | HSD17B10 (0.61) | KMT2AMEN1KDM4ETSHRHPGD | |
| SCHEMBL4991673 | 0.75 | SMN1; SMN2 (0.73) | KMT2AMEN1HPGDSMN1; SMN2LMNA | |
| SCHEMBL20830056 | 0.74 | HPGD (0.72) | KMT2AMEN1KDM4ETSHRHPGD | |
| SCHEMBL20828646 | 0.74 | HPGD (0.73) | KMT2AMEN1KDM4EHPGDLMNA | |
| SCHEMBL2728973 | 0.74 | AURKA (0.64) | KDRKDM4EHPGDAURKARPS6KB1 | |
| SCHEMBL1714616 | 0.74 | KDR (0.54) | KDRKMT2AMEN1KDM4ETSHR | |
| SCHEMBL12700347 | 0.74 | HPGD (0.72) | KMT2AMEN1KDM4EHPGDLMNA | |
| SCHEMBL8636561 | 0.73 | MAPK8 (0.67) | KMT2AMEN1KDM4ETSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996033190-A1 | QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THE RESULTANT INTERMEDIATES, THEIR USE AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL UCLAF (FR) | 1996-10-24 | — | — | WO | disclosed |