Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CFD | P00746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ASPH | Q12797 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2691864 | 0.85 | HSD17B10 (0.81) | HSD17B10ALDH1A1HPGDPOLBCTDSP1 | |
| SCHEMBL27327995 | 0.85 | HSD17B10 (0.65) | HSD17B10ALDH1A1HPGDPOLBCTDSP1 | |
| SCHEMBL12725538 | 0.84 | HIF1A (0.53) | HSD17B10ALDH1A1HPGDPOLBCTDSP1 | |
| SCHEMBL464918 | 0.84 | HPGD (0.63) | HSD17B10ALDH1A1HPGDPOLBCTDSP1 | |
| SCHEMBL2754257 | 0.84 | HSD17B10 (0.63) | HSD17B10ALDH1A1HPGDPOLBCTDSP1 | |
| SCHEMBL30311518 | 0.84 | HSD17B10 (0.63) | HSD17B10ALDH1A1HPGDPOLBCTDSP1 | |
| SCHEMBL28644608 | 0.83 | ADRA1D (0.58) | HSD17B10ALDH1A1HPGDPOLBCTDSP1 | |
| SCHEMBL22854454 | 0.83 | ALDH1A1 (0.68) | HSD17B10ALDH1A1HPGDPOLBCTDSP1 | |
| SCHEMBL12608931 | 0.83 | RXFP1 (0.54) | HSD17B10ALDH1A1HPGDL3MBTL1RXFP1 | |
| SCHEMBL5707716 | 0.82 | HSD17B10 (0.61) | HSD17B10ALDH1A1HPGDPOLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947690-B | Preparation method of indazole molecular building block and application of indazole molecular building block in drug synthesis | 安徽医科大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-114716438-B | Benzo [7,8] indolizine [1,2-c ] quinoline skeleton derivative and synthetic method thereof | 常州大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-114716438-A | Derivative with benzo [7,8] indolizine [1,2-c ] quinoline skeleton and synthetic method thereof | 常州大学 | 2022-07-08 | — | — | CN | disclosed |
| US-20150080351-A1 | ARYL SULFONAMIDES | CHEMOCENTRYX, INC. | 2015-03-19 | — | — | US | disclosed |
| US-20130267492-A1 | ARYL SULFONAMIDES | CHEMOCENTRYX, INC. (US) | 2013-10-10 | — | — | US | disclosed |
| US-8211896-B2 | Aryl sulfonamides | CHEMOCENTRYX, INC. (US) | 2012-07-03 | — | — | US | disclosed |
| US-20120101097-A9 | ARYL SULFONAMIDES | UNGASHE SOLOMON (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120014997-A1 | ARYL SULFONAMIDES | UNGASHE SOLOMON (US) | 2012-01-19 | — | — | US | disclosed |
| EP-2392328-A1 | Compounds for modulating TRPV3 Function | Hydra Biosciences, Inc. (US) | 2011-12-07 | — | — | EP | disclosed |
| US-20110201610-A1 | ARYL SULFONAMIDES | UNGASHE SOLOMON | 2011-08-18 | — | — | US | disclosed |
| US-7906655-B2 | 5,5'-(1,2-ethynediyl)bis(2-((2S)-1-((2R)-2-phenylpropanoyl)-2-pyrrolidinyl)-1H-benzimidazole); inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV); useful in establishing or determining the binding site of other antiviral compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-03-15 | — | — | US | disclosed |
| US-20110021523-A1 | ARYL SULFONAMIDES | CHEMOCENTRYX, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| CN-101012170-B | N-arylation method in water solution | UNIV SUN YAT SEN | 2010-12-08 | — | — | CN | disclosed |
| US-20100068176-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2010-03-18 | — | — | US | disclosed |
| CN-101012170-A | N-arylation method in water solution | UNIV SUN YAT SEN (CN) | 2007-08-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068176-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, PYGL, HCCS | HSD17B10 1305/4885ALDH1A1 1144/4885HPGD 1775/4885 |
| US-20120014997-A1 | ARYL SULFONAMIDES | CCR9, CCR1, CCR2 | HSD17B10 2850/4885ALDH1A1 1655/4885HPGD 3897/4885 |
| US-20110021523-A1 | ARYL SULFONAMIDES | CCR9, CCR1, CCR2 | HSD17B10 2850/4885ALDH1A1 1655/4885HPGD 3897/4885 |
| US-20110201610-A1 | ARYL SULFONAMIDES | CCR2, CCL2, CX3CR1 | HSD17B10 2344/4885ALDH1A1 1258/4885HPGD 1168/4885 |
| US-20150080351-A1 | ARYL SULFONAMIDES | CCR9, CCR1, CCR2 | HSD17B10 2850/4885ALDH1A1 1655/4885HPGD 3897/4885 |
| US-20120101097-A9 | ARYL SULFONAMIDES | CCR2, CCL2, CX3CR1 | HSD17B10 2344/4885ALDH1A1 1258/4885HPGD 1168/4885 |
| US-20130267492-A1 | ARYL SULFONAMIDES | CCR9, CCR1, CCR2 | HSD17B10 2850/4885ALDH1A1 1655/4885HPGD 3897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.