SCHEMBL9284249

SCHEMBL9284249

C=CC[SiH2]c1ccccc1-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
DPP4 P27487 1/20 0.35
ALDH1A1 P00352 5/20 0.34
HSD17B10 Q99714 2/20 0.34
HPGD P15428 2/20 0.34
BCL2L1 Q07817 1/20 0.34
CYP2A6 P11509 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 2/20 0.33
HTR7 P34969 1/20 0.33
KMT2A Q03164 3/20 0.32
GAA P10253 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MAPT P10636 1/20 0.32
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
BACE1 P56817 1/20 0.31
MMP9 P14780 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1732809 0.72 ALDH1A1 (0.40) ALDH1A1
SCHEMBL463323 0.70 ALDH1A1 (0.36) ALDH1A1HTT
Biphenyl SCHEMBL28773768 0.70 ALDH1A1 (0.45) ALDH1A1HSD17B10HPGDBCL2L1MAPK1
SCHEMBL16756188 0.69 ALDH1A1 (0.46) DPP4ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL28676010 0.69 ALDH1A1 (0.46) DPP4ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL29351292 0.69 ALDH1A1 (0.46) DPP4ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL4079881 0.69 ALDH1A1 (0.39) ALDH1A1
Biphenyl SCHEMBL28806829 0.67 ALDH1A1 (0.41) ALDH1A1HPGDBCL2L1HTTGAA
SCHEMBL7105248 0.67 DPP4 (0.50) ADRB2ADRB1DPP4HTR7KMT2A
Butadiene SCHEMBL9807163 0.67 ALDH1A1 (0.48) ADRB2ADRB1DPP4ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995016671-A1 TRIFLATE-MEDIATED PREPARATION AND USE OF IODONIUM COMPOUNDS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1995-06-22 WO disclosed