SCHEMBL463323

SCHEMBL463323

C=CC[SiH2]c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.31
AKT1 P31749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6864487 0.76 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19
SCHEMBL6401559 0.75 ALDH1A1 (0.45) ALDH1A1TSHR
SCHEMBL10456560 0.73
SCHEMBL8517452 0.73 LPL (0.39) ALDH1A1TSHR
SCHEMBL9717044 0.71 MAOB (0.32)
SCHEMBL7789592 0.71 MAOB (0.32) ALDH1A1
SCHEMBL9441984 0.71 MAOB (0.32)
SCHEMBL9284249 0.70 ADRB2 (0.37) ALDH1A1HTT
SCHEMBL8518392 0.70 THRB (0.46) ALDH1A1
Biphenyl SCHEMBL28773768 0.70 ALDH1A1 (0.45) ALDH1A1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 402 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114377727-B Embedding type metal catalyst 安徽壹石通材料科学研究院有限公司 2023-08-01 CN claimed
CN-114377727-A Embedded metal catalyst 安徽壹石通材料科学研究院有限公司 2022-04-22 CN claimed
CN-113991094-A Heteroatom in-situ doped porous carbon composite lithium cathode and preparation method and application thereof 重庆硕盈峰新能源科技有限公司 2022-01-28 CN claimed
CN-113991093-A Preparation of heteroatom in-situ doped porous carbon and application of heteroatom in high-rate sodium ion battery 重庆硕盈峰新能源科技有限公司 2022-01-28 CN claimed
CN-104185628-A Arylalkyloxy pyrimidine derivative, pesticide for agricultural and horticultural use containing arylalkyloxy pyrimidine derivative as active ingredient, and use of same NIHON NOHYAKU CO LTD 2014-12-03 CN claimed
CN-102307863-B Pyrimidine derivatives, horticultural insecticides comprising said derivatives and method of use thereof NIHON NOHYAKU CO LTD 2014-05-07 CN claimed
CN-103339114-A Benzyloxypyrimidine derivative, agricultural/horticultural insecticide comprising derivative and method for using same NIHON NOHYAKU CO LTD 2013-10-02 CN claimed
CN-103038208-A Process for the preparation of 1-aryl-pyrazol-3-one intermediates useful in the synthesis of sigma receptors inhibitors ESTEVE QUIMICA SA 2013-04-10 CN claimed
CN-102307863-A Pyrimidine derivatives, horticultural insecticides comprising said derivatives and method of use thereof NIHON NOHYAKU CO LTD 2012-01-04 CN claimed
US-8026329-B2 Polycarbosilane and method of producing the same TOKAI CARBON KOREA CO., LTD. (KR) 2011-09-27 US claimed
EP-0701553-B1 ARYLPYRAZOLE FUNGICIDES RHONE POULENC AGROCHIMIE (FR) 1997-10-01 EP claimed
EP-0654495-A1 Photoconductive film formed from a grafted silane polymer; process for preparing and process for the formation of an electrostatic image of this film and an optical valve based on this film FRANCE TELECOM (FR) 1995-05-24 EP claimed
CN-1079735-A Arylpyrazole mycocide ENERGY BIOSYSTEMS CORP (FR) 1993-12-22 CN claimed
US-5162465-A Preparation of homopolymers and copolymers of propene using a Ziegler-Natta catalyst system BASF AKTIENGESELLSCHAFT (DE) 1992-11-10 US claimed
EP-0502677-A1 Photosensitizers for polysilanes International Business Machines Corporation (US) 1992-09-09 EP claimed
EP-0166516-B1 NOVEL PHENYL-SUBSITUTED SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-08 EP claimed
US-5089648-A Using tetrakis/triethylphosphine/nickel polymerization catalyst ETHYL CORPORATION (US) 1992-02-18 US claimed
US-4751170-A Silylation method onto surface of polymer membrane and pattern formation process by the utilization of silylation method NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1988-06-14 US claimed
EP-0207977-A1 SURFACE TREATMENT AGENTS AND POLYMERS KSV-Chemicals Oy (FI) 1987-01-14 EP claimed
WO-1986004063-A1 SURFACE TREATMENT AGENTS AND POLYMERS KSV-CHEMICALS OY (FI) 1986-07-17 WO claimed