Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2461750 | 0.90 | XDH (0.48) | XDHTNKSPARP1DHFRGABRA1 | |
| SCHEMBL9284341 | 0.88 | DHFR (0.43) | XDHDHFRGABRA1GABRB2MEN1 | |
| SCHEMBL11660795 | 0.84 | DHFR (0.46) | XDHTNKSPARP1DHFRGABRA1 | |
| SCHEMBL9285299 | 0.82 | XDH (0.42) | XDHTNKSPARP1DHFRGABRA1 | |
| SCHEMBL18657227 | 0.81 | GABRA1 (0.52) | XDHTNKSPARP1DHFRGABRA1 | |
| SCHEMBL9319191 | 0.80 | TNKS (0.56) | XDHTNKSPARP1GABRA1GABRB2 | |
| SCHEMBL27683623 | 0.80 | HSPA5 (0.49) | TNKSPARP1DHFRMEN1GAA | |
| SCHEMBL11660801 | 0.79 | GABRA1 (0.45) | XDHTNKSPARP1DHFRGABRA1 | |
| SCHEMBL9489328 | 0.79 | DHFR (0.48) | XDHTNKSPARP1DHFRGABRA1 | |
| SCHEMBL11557270 | 0.79 | DHFR (0.46) | XDHTNKSPARP1DHFRGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387266-A | Detergent-dispersant additives for fuels and lubricants | ETHYL CORPORATION (US) | 1995-02-07 | — | — | US | claimed |