SCHEMBL9285455

SCHEMBL9285455

C=C(CCCC=CF)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 4/20 0.33
PPARG P37231 4/20 0.33
HSD17B10 Q99714 4/20 0.33
ALOX15 P16050 3/20 0.33
CYP19A1 P11511 3/20 0.33
KMT2A Q03164 3/20 0.33
PPARD Q03181 3/20 0.33
PPARA Q07869 3/20 0.33
F7 P08709 3/20 0.33
F3 P13726 3/20 0.33
TBXAS1 P24557 2/20 0.33
ALDH1A1 P00352 2/20 0.33
ADORA3 P0DMS8 2/20 0.33
PTGS1 P23219 2/20 0.33
RXRA P19793 1/20 0.33
OXER1 Q8TDS5 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
MAPT P10636 3/20 0.32
FABP4 P15090 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15609460 0.87 ALOX15 (0.35) HSD17B10ALOX15TET2
SCHEMBL7596072 0.79 GABRR1 (0.38) TOP1PPARGHSD17B10ALOX15CYP19A1
SCHEMBL8460321 0.78 TOP1 (0.48) TOP1PPARGHSD17B10ALOX15CYP19A1
SCHEMBL1824152 0.76 HIF1A (0.41) HSD17B10ALOX15TBXAS1MAPTLMNA
SCHEMBL2048074 0.76 HIF1A (0.41) HSD17B10ALOX15TBXAS1MAPTLMNA
SCHEMBL2119324 0.76 MAPT (0.52) HSD17B10ALOX15TBXAS1ALDH1A1MAPT
SCHEMBL5925120 0.75 FNTA (0.43) TOP1PPARGHSD17B10ALOX15CYP19A1
Maleic Acid SCHEMBL23702521 0.75 ALOX15 (0.34) TOP1PPARGHSD17B10ALOX15CYP19A1
SCHEMBL11550565 0.75 TOP1 (0.65) TOP1PPARGHSD17B10ALOX15CYP19A1
SCHEMBL720674 0.74 ALOX15 (0.35) HSD17B10ALOX15TBXAS1MAPTTET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0414155-B1 Soilresisting agent ASAHI GLASS CO LTD (JP) 1995-03-08 EP disclosed
US-5100954-A SOILRESISTING AGENT COPOLYMER OF FLUORINATED, UNSATURATED URETHANE AND UNSATURATED MONOMER ASAHI GLASS COMPANY LTD. (JP) 1992-03-31 US disclosed
EP-0414155-A1 Soilresisting agent ASAHI GLASS COMPANY LTD. (JP) 1991-02-27 EP disclosed