Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | HTR6 | P50406 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444672 | 0.98 | KDM4E (0.68) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8440798 | 0.98 | KDM4E (0.68) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8444727 | 0.98 | KDM4E (0.68) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8442541 | 0.98 | KDM4E (0.68) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8445695 | 0.98 | KDM4E (0.68) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8441371 | 0.98 | KDM4E (0.68) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8445875 | 0.98 | KDM4E (0.68) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8998008 | 0.95 | KDM4E (0.72) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL8552151 | 0.89 | ALDH1A1 (0.71) | KDM4EPOLBALDH1A1HTTTSHR | |
| SCHEMBL5409935 | 0.84 | CHRNB2 (0.60) | KDM4EPOLBALDH1A1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501165-B | Asymmetric synthesis method of chiral tetrahydrocarbazole derivative | 合肥工业大学 | 2020-03-31 | — | — | CN | disclosed |
| CN-107501165-A | The method of asymmetric synthesis of chiral compounds | 合肥工业大学 | 2017-12-22 | — | — | CN | disclosed |
| EP-3230463-A1 | RAPID PRETREATMENT | Sweetwater Energy, Inc. (US) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016094594-A1 | RAPID PRETREATMENT | SWEETWATER ENERGY, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20080090871-A1 | CANNABIMIMETIC INDOLE DERIVATIVES | MAKRIYANNIS ALEXANDROS | 2008-04-17 | — | — | US | disclosed |
| US-7241799-B2 | Cannabimimetic indole derivatives | UNIVERSITY OF CONNECTICUT (US) | 2007-07-10 | — | — | US | disclosed |
| EP-1702617-A1 | Cannabimimetic indole derivatives | THE UNIVERSITY OF CONNECTICUT (US) | 2006-09-20 | — | — | EP | disclosed |
| EP-1223929-B1 | CANNABIMIMETIC INDOLE DERIVATIVES | UNIV CONNECTICUT (US) | 2006-08-23 | — | — | EP | disclosed |
| US-20050119234-A1 | Cannabimimetic indole derivatives | UNIVERSITY OF CONNECTICUT (US) | 2005-06-02 | — | — | US | disclosed |
| US-6900236-B1 | Cannabimimetic indole derivatives | UNIVERSITY OF CONNECTICUT (US) | 2005-05-31 | — | — | US | disclosed |
| US-6872835-B2 | Process for preparation of fused pyrroles | JAPAN SCIENCE & TECHNOLOGY CORPORATION (JP) | 2005-03-29 | — | — | US | disclosed |
| EP-1302459-B1 | PROCESSES FOR PREPARATION OF FUSED PYRROLES | JAPAN SCIENCE & TECH AGENCY (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-20040049054-A1 | Process for preparation of fused pyrroles | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1302459-A1 | PROCESSES FOR PREPARATION OF FUSED PYRROLES | Japan Science and Technology Corporation (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-6433001-B1 | SEPTIC SHOCK, ALLERGIC RHINITIS, RHEUMATIC ARTHRITIS, ADULT RESPIRATORY DISTRESS SYNDROME, BRONCHIAL ASTHMA, TRAUMA, AND PANCREATITIS TREATMENT | ELI LILLY AND COMPANY | 2002-08-13 | — | — | US | disclosed |
| EP-0675110-B1 | 1H-Indole-3-glyoxylamide sPLA2 inhibitors | LILLY CO ELI (US) | 2002-07-10 | — | — | EP | disclosed |
| US-5919810-A | SEPTIC SHOCK | ELI LILLY AND COMPANY (US) | 1999-07-06 | — | — | US | disclosed |
| EP-0022634-B1 | ACYLATED INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS AND DRUGS COMPRISING THEM | TEIJIN LIMITED (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0022634-A1 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them | TEIJIN LIMITED (JP) | 1981-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119234-A1 | Cannabimimetic indole derivatives | CNR2, CNR1, HTR2C | KDM4E 3392/4885POLB 4672/4885ALDH1A1 3887/4885 |
| US-20040049054-A1 | Process for preparation of fused pyrroles | IDO1, IDO2, PAH | KDM4E 360/4885POLB 1923/4885ALDH1A1 1591/4885 |
| US-20080090871-A1 | CANNABIMIMETIC INDOLE DERIVATIVES | CNR2, CNR1, GPR34 | KDM4E 3526/4885POLB 4412/4885ALDH1A1 3604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.