Hydroquinone

Hydroquinone

SCHEMBL9285995

Cc1c(O)cccc1O.Oc1ccc(O)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.62
ATM Q13315 1/20 0.62
ACHE P22303 3/20 0.50
ALDH1A1 P00352 4/20 0.47
CA2 P00918 4/20 0.47
LMNA P02545 3/20 0.47
HPGD P15428 3/20 0.47
ALOX15 P16050 3/20 0.47
RECQL P46063 3/20 0.47
HSD17B10 Q99714 3/20 0.47
CA1 P00915 3/20 0.47
CA12 O43570 3/20 0.47
CA3 P07451 3/20 0.47
CYP3A4 P08684 3/20 0.47
CA4 P22748 3/20 0.47
CA14 Q9ULX7 3/20 0.47
KDM4E B2RXH2 2/20 0.47
NPC1 O15118 2/20 0.47
GMNN O75496 2/20 0.47
MAPT P10636 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4873527 0.91 TRPA1 (0.72) TRPA1ATMACHEALDH1A1CA2
SCHEMBL33721 0.91
Hydrochloric Acid SCHEMBL7792394 0.88 TRPA1 (0.68) TRPA1ATMACHEALDH1A1CA2
SCHEMBL30632314 0.88 TRPA1 (0.68) TRPA1ATMACHEALDH1A1CA2
Potassium SCHEMBL30632313 0.88 TRPA1 (0.68) TRPA1ATMACHEALDH1A1CA2
SCHEMBL29085428 0.88 TRPA1 (0.68) TRPA1ATMACHEALDH1A1CA2
Resorcinol SCHEMBL8159309 0.83 ALDH1A1 (0.63) TRPA1ATMACHEALDH1A1CA2
Formaldehyde SCHEMBL9393871 0.82 TRPA1 (0.62) TRPA1ATMACHEALDH1A1CA2
Hydroquinone SCHEMBL10426480 0.81 ACHE (0.56) TRPA1ATMACHEALDH1A1CA2
P-Cresol SCHEMBL8942720 0.81 TRPA1 (0.74) TRPA1ATMACHEALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5460937-A Forming additive with solid hydrophilic material to add to aqueous silver halide emulsion EASTMAN KODAK COMPANY (US) 1995-10-24 US disclosed
US-4193801-A DISSOLVING WATER-INSOLUBLE ADDITIVES IN A MELT OF ACID IMIDE OR DERIVATIVE CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-03-18 US disclosed