Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9289218 | 0.85 | CSNK2A2 (0.66) | CSNK2A2CSNK2BCSNK2A1CSNK2A3DPP4 | |
| SCHEMBL12653045 | 0.85 | CSNK2A2 (0.49) | CSNK2A2CSNK2BCSNK2A1CSNK2A3PTPN1 | |
| SCHEMBL9287839 | 0.82 | DPP4 (0.63) | CSNK2A2CSNK2BCSNK2A1CSNK2A3S1PR4 | |
| SCHEMBL23862755 | 0.80 | CSNK2A2 (0.55) | CSNK2A2CSNK2BCSNK2A1CSNK2A3S100A4 | |
| SCHEMBL9285164 | 0.80 | ALDH1A1 (0.49) | CSNK2A2CSNK2BCSNK2A1CSNK2A3ALDH1A1 | |
| SCHEMBL8819020 | 0.80 | CSNK2A2 (0.48) | CSNK2A2CSNK2BCSNK2A1CSNK2A3DPP4 | |
| SCHEMBL9285171 | 0.80 | CSNK2A2 (0.48) | CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT | |
| SCHEMBL2393195 | 0.78 | CXCL8 (0.43) | PTPN1DPP4CNR2CHRM1ALDH1A1 | |
| SCHEMBL381603 | 0.78 | PTPN1 (0.56) | PTPN1DPP4S100A4CNR2ALDH1A1 | |
| SCHEMBL29983105 | 0.78 | PTPN1 (0.56) | PTPN1DPP4S100A4CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | BACE1, STS, APP | CSNK2A2 682/4885CSNK2B 358/4885CSNK2A1 613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.