Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 12/20 | 0.91 |
| ▸ | GABRD | O14764 | 12/20 | 0.91 |
| ▸ | GABRA1 | P14867 | 12/20 | 0.91 |
| ▸ | GABRB1 | P18505 | 12/20 | 0.91 |
| ▸ | GABRG2 | P18507 | 12/20 | 0.91 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.91 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.91 |
| ▸ | GABRA3 | P34903 | 12/20 | 0.91 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.91 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.91 |
| ▸ | GABRA4 | P48169 | 12/20 | 0.91 |
| ▸ | GABRE | P78334 | 12/20 | 0.91 |
| ▸ | GABRA6 | Q16445 | 12/20 | 0.91 |
| ▸ | GABRG1 | Q8N1C3 | 12/20 | 0.91 |
| ▸ | GABRG3 | Q99928 | 12/20 | 0.91 |
| ▸ | GABRQ | Q9UN88 | 12/20 | 0.91 |
| ▸ | IDO1 | P14902 | 1/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521035 | 0.95 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21321452 | 0.84 | GABRP (0.75) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27917521 | 0.81 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Carbazole SCHEMBL27757289 | 0.79 | ALDH1A1 (0.67) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28147848 | 0.78 | ALDH1A1 (0.71) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2689187 | 0.78 | ALDH1A1 (0.71) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2216848 | 0.78 | ALDH1A1 (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10644773 | 0.78 | GABRA1 (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10645756 | 0.78 | ALDH1A1 (0.66) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10646297 | 0.78 | ALDH1A1 (0.66) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543519-A | 3-aryl or 3-hetaryl-β-carbolines, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-08-06 | — | — | US | disclosed |