Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 4/20 | 0.35 |
| ▸ | CES1 | P23141 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | PAM | P19021 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441850 | 0.81 | ALDH1A1 (0.37) | MAPTKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL1325862 | 0.80 | ZDHHC7 (0.41) | MAPTKMT2AFAAHLMNAALDH1A1 | |
| SCHEMBL21646318 | 0.78 | ZDHHC7 (0.43) | MAPTFAAHLMNA | |
| SCHEMBL28288321 | 0.78 | ZDHHC7 (0.43) | MAPTFAAHLMNA | |
| SCHEMBL29374123 | 0.78 | ZDHHC7 (0.43) | MAPTFAAHLMNA | |
| SCHEMBL17079750 | 0.78 | ZDHHC7 (0.43) | MAPTFAAHLMNA | |
| SCHEMBL9562158 | 0.78 | CA2 (0.40) | KMT2ALMNAALDH1A1 | |
| SCHEMBL4611750 | 0.76 | MAPT (0.43) | MAPTKMT2ADGKAFAAHCES2 | |
| SCHEMBL537543 | 0.75 | GAA (0.43) | KMT2ALMNAALDH1A1 | |
| SCHEMBL1752394 | 0.75 | ALDH1A1 (0.38) | MAPTKMT2ALMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447942-A | Treatment of bronchoconstriction | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1995-09-05 | — | — | US | disclosed |