Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994547 | 1.00 | ACE (0.54) | ACELMNASMN1; SMN2 | |
| SCHEMBL7282100 | 0.89 | ACE (0.52) | ACELMNA | |
| SCHEMBL7282095 | 0.89 | ACE (0.52) | ACELMNA | |
| SCHEMBL8994570 | 0.89 | FKBP1A (0.47) | ACELMNASMN1; SMN2 | |
| SCHEMBL8994567 | 0.89 | FKBP1A (0.47) | ACELMNASMN1; SMN2 | |
| SCHEMBL8994537 | 0.83 | ACE (0.52) | ACELMNASMN1; SMN2 | |
| SCHEMBL8994536 | 0.83 | ACE (0.52) | ACELMNASMN1; SMN2 | |
| SCHEMBL8994534 | 0.83 | ACE (0.52) | ACELMNASMN1; SMN2 | |
| SCHEMBL7282612 | 0.80 | FKBP1A (0.48) | ACE | |
| SCHEMBL7282610 | 0.80 | FKBP1A (0.48) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411974-A | Thiazoline derivatives, treatment of amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| US-5212191-A | Thiazoline derivatives for treatment of amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |