Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 14/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11673411 | 0.85 | GRM5 (0.49) | GRM5ALOX5APFEN1TRPA1PPARG | |
| SCHEMBL12945561 | 0.79 | LMNA (0.40) | GRM5ALOX5APFEN1CTSAMET | |
| SCHEMBL9289362 | 0.78 | GRM5 (0.44) | GRM5ALOX5APFEN1TRPA1 | |
| SCHEMBL9258487 | 0.75 | TRPA1 (0.38) | CTSATRPA1MET | |
| SCHEMBL9288060 | 0.75 | ALOX5AP (0.46) | GRM5ALOX5APFEN1TRPA1 | |
| SCHEMBL3159085 | 0.75 | DPP4 (0.34) | — | |
| SCHEMBL31708384 | 0.75 | ALOX5AP (0.46) | GRM5ALOX5APFEN1TRPA1 | |
| SCHEMBL27405271 | 0.74 | RXRA (0.42) | MET | |
| SCHEMBL24526794 | 0.74 | PTGER1 (0.55) | GRM5PPARGPPARA | |
| SCHEMBL29759316 | 0.74 | PTGER1 (0.55) | GRM5PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | BACE1, STS, APP | GRM5 2955/4885ALOX5AP 1427/4885FEN1 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.