Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 2/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782430 | 0.80 | MAPT (0.35) | FFAR4MEN1KMT2A | |
| SCHEMBL769717 | 0.78 | SMN1; SMN2 (0.40) | FFAR4KCNH2TSHRMEN1KMT2A | |
| SCHEMBL782510 | 0.78 | MEN1 (0.33) | FFAR4TSHRMEN1KMT2A | |
| SCHEMBL782328 | 0.76 | KCNH2 (0.33) | KCNH2MEN1KMT2A | |
| SCHEMBL782549 | 0.76 | MAPK8 (0.39) | KCNH2CYP2D6MEN1KMT2A | |
| SCHEMBL782542 | 0.74 | KMT2A (0.45) | EPHX2MEN1KMT2A | |
| SCHEMBL782578 | 0.74 | — | — | |
| SCHEMBL782506 | 0.74 | ALDH1A1 (0.32) | MEN1KMT2A | |
| SCHEMBL782518 | 0.74 | L3MBTL1 (0.40) | KCNH2MEN1KMT2A | |
| SCHEMBL782638 | 0.74 | OPRM1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069008-A1 | 3-SUBSTITUTED SPIROHETEROCYCLIC FURAN AND THIOFURAN DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |