SCHEMBL9290205

SCHEMBL9290205

CON1CCC(N)(OC(=O)Cc2cc(C)c(C)cc2C)CC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
PLA2G1B P04054 1/20 0.31
POLB P06746 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9286903 0.82 FFAR4 (0.32)
SCHEMBL782618 0.81 STS (0.36) L3MBTL1
SCHEMBL782518 0.81 L3MBTL1 (0.40) L3MBTL1POLB
SCHEMBL9286734 0.80 ALDH1A1 (0.31) L3MBTL1
SCHEMBL9290057 0.80
SCHEMBL46128 0.78 L3MBTL1 (0.34) L3MBTL1PLA2G1BPOLBATG4B
SCHEMBL12071076 0.71 OPRM1 (0.33) L3MBTL1
SCHEMBL46096 0.71 OPRM1 (0.35) L3MBTL1
SCHEMBL9286737 0.70 HDAC3 (0.34) L3MBTL1POLB
SCHEMBL9286636 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012069008-A1 3-SUBSTITUTED SPIROHETEROCYCLIC FURAN AND THIOFURAN DIONE DERIVATIVES USEFUL AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2012-05-31 WO disclosed
WO-2010135914-A1 NEW SPIROHETEROCYCLIC FURAN AND THIOFURAN DIONE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2010-12-02 WO disclosed