Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12561287 | 0.89 | PDE6D (0.46) | PDE6DHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL9290293 | 0.85 | PDE6D (0.55) | PDE6DALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9290289 | 0.82 | PDE6D (0.65) | PDE6DHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL9290298 | 0.81 | PDE6D (0.44) | PDE6DALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9290294 | 0.81 | KMT2A (0.59) | PDE6DHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL9290364 | 0.80 | PDE6D (0.50) | PDE6DALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL12561292 | 0.76 | PDE6D (0.41) | PDE6DALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9290305 | 0.74 | HPGD (0.43) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9290446 | 0.73 | PDE6D (0.56) | PDE6DHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL12561289 | 0.73 | PDE6D (0.56) | PDE6DALDH1A1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2458941-A1 | OPTICAL FILTER | Adeka Corporation (JP) | 2012-05-30 | — | — | EP | disclosed |