SCHEMBL9290299

SCHEMBL9290299

CC(C)(C)c1ccc2c3c(cccc13)C(=O)N2c1ccc(C(F)(F)F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.40
NR1H3 Q13133 1/20 0.40
HIF1A Q16665 1/20 0.38
ALDH1A1 P00352 4/20 0.38
USP2 O75604 4/20 0.38
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
RORC P51449 1/20 0.37
KDM4E B2RXH2 3/20 0.37
GALR3 O60755 1/20 0.37
HTR4 Q13639 1/20 0.37
KEAP1 Q14145 2/20 0.36
NFE2L2 Q16236 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9290292 0.86 ALDH1A1 (0.49) PDE6DALDH1A1USP2KMT2AMEN1
SCHEMBL9290295 0.83 KMT2A (0.48) PDE6DNR1H3ALDH1A1KMT2AMEN1
SCHEMBL9290416 0.82 PDE6D (0.48) PDE6DNR1H3HIF1AALDH1A1USP2
SCHEMBL9290300 0.81 PDE6D (0.44) PDE6DALDH1A1USP2KMT2AMEN1
SCHEMBL9290378 0.81 PDE6D (0.52) PDE6DNR1H3HIF1AALDH1A1USP2
SCHEMBL12561357 0.80 ALDH1A1 (0.47) PDE6DNR1H3ALDH1A1USP2KMT2A
SCHEMBL9290304 0.80 MEN1 (0.44) PDE6DALDH1A1USP2KMT2AMEN1
SCHEMBL9290432 0.78 PDE6D (0.49) PDE6DNR1H3ALDH1A1USP2KMT2A
SCHEMBL9290289 0.78 PDE6D (0.65) PDE6DNR1H3ALDH1A1KMT2AMEN1
SCHEMBL9290435 0.78 KMT2A (0.48) PDE6DNR1H3KMT2AMEN1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152538-A1 OPTICAL FILTER C1R, CBR3, CBR1 PDE6D 69/4885NR1H3 152/4885HIF1A 1897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.