SCHEMBL9290293

SCHEMBL9290293

C=Cc1cc2c3c(cccc3c1)C(=O)N2c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.55
HSPA1A P0DMV8 1/20 0.43
PABPC1 P11940 1/20 0.43
ALDH1A1 P00352 6/20 0.43
GAA P10253 2/20 0.43
CES2 O00748 1/20 0.43
BCHE P06276 1/20 0.43
CES1 P23141 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
KMT2A Q03164 6/20 0.43
KDM4E B2RXH2 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
USP2 O75604 2/20 0.43
MAPT P10636 2/20 0.43
HTT P42858 2/20 0.43
CA12 O43570 2/20 0.43
CA9 Q16790 2/20 0.43
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9290298 0.90 PDE6D (0.44) PDE6DALDH1A1GAAKMT2AKDM4E
SCHEMBL9290364 0.89 PDE6D (0.50) PDE6DHSPA1APABPC1ALDH1A1GAA
SCHEMBL12561289 0.87 PDE6D (0.56) PDE6DHSPA1APABPC1ALDH1A1GAA
SCHEMBL9290306 0.85 PDE6D (0.45) PDE6DALDH1A1KMT2AKDM4ESMN1; SMN2
SCHEMBL9290294 0.85 KMT2A (0.59) PDE6DALDH1A1KMT2AKDM4EMAPT
SCHEMBL12561292 0.84 PDE6D (0.41) PDE6DALDH1A1GAAKMT2AKDM4E
SCHEMBL9290287 0.79 PDE6D (0.82) PDE6DALDH1A1GAACES2BCHE
SCHEMBL12561294 0.77 PDE6D (0.51) PDE6DALDH1A1GAACES2BCHE
SCHEMBL299841 0.73 ALDH1A1 (0.71) PDE6DHSPA1APABPC1ALDH1A1GAA
SCHEMBL9290303 0.73 ALDH1A1 (0.47) PDE6DALDH1A1KMT2AKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed