SCHEMBL9290304

SCHEMBL9290304

Cc1cc(C)cc(N2C(=O)c3cccc4c(C(C)(C)C)ccc2c34)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.44
KMT2A Q03164 8/20 0.44
USP2 O75604 6/20 0.44
KEAP1 Q14145 3/20 0.44
NFE2L2 Q16236 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 3/20 0.38
RORC P51449 1/20 0.38
MAPT P10636 5/20 0.38
HTT P42858 4/20 0.38
TP53 P04637 1/20 0.38
HPGD P15428 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
HBB P68871 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PDE6D O43924 1/20 0.36
PKM P14618 1/20 0.36
GRM5 P41594 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9290292 0.85 ALDH1A1 (0.49) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL9290299 0.80 PDE6D (0.40) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL9290295 0.80 KMT2A (0.48) MEN1KMT2AALDH1A1KDM4ERORC
SCHEMBL9290296 0.80 KMT2A (0.38) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL9290386 0.80 PDE6D (0.48) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL12561358 0.80 MEN1 (0.47) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL9290300 0.78 PDE6D (0.44) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL12601548 0.76 PKM (0.58) ALDH1A1KDM4ETP53CASP1PKM
SCHEMBL9290454 0.76 MEN1 (0.42) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL9290430 0.75 GRM5 (0.47) MEN1KMT2AUSP2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152538-A1 OPTICAL FILTER C1R, CBR3, CBR1 MEN1 3537/4885KMT2A 4130/4885USP2 3865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.