Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 5/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29349036 | 0.78 | ALDH1A1 (0.46) | CA12CA1CA2CA9CA14 | |
| SCHEMBL29349037 | 0.78 | CA12 (0.36) | CA12CA1CA2CA9CA14 | |
| SCHEMBL8306550 | 0.78 | MAP3K5 (0.40) | CA12CA1CA2CA9CA14 | |
| SCHEMBL19817380 | 0.76 | PTGS1 (0.49) | CA12CA1CA2CA9CA14 | |
| SCHEMBL13890715 | 0.74 | ALDH1A1 (0.39) | CA12CA1CA2CA9CA14 | |
| SCHEMBL15212468 | 0.74 | OPRM1 (0.41) | CA1CA2F10KDM4E | |
| SCHEMBL15212518 | 0.74 | CA12 (0.37) | CA12CA1CA2CA9CA14 | |
| SCHEMBL31068240 | 0.73 | ALDH1A1 (0.52) | — | |
| SCHEMBL85596 | 0.73 | ALDH1A1 (0.52) | — | |
| SCHEMBL12544980 | 0.70 | F10 (0.38) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129373-B2 | Carbonyl compounds | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20100256131-A1 | CARBONYL COMPOUNDS | TSAKLAKIDIS CHRISTOS | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256131-A1 | CARBONYL COMPOUNDS | F2, F11, PDHX | CA12 1090/4885CA1 1847/4885CA2 2538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.