Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL17667733 | 0.99 | CHRNA7 (0.47) | CHRNA7CHRM2CHRM1PABPC1BLM | |
| Bromide SCHEMBL8509379 | 0.99 | CHRNA7 (0.47) | CHRNA7CHRM2CHRM1PABPC1BLM | |
| Bromide SCHEMBL17667731 | 0.99 | CHRNA7 (0.47) | CHRNA7CHRM2CHRM1PABPC1BLM | |
| SCHEMBL9290260 | 0.86 | CHRM2 (0.61) | CHRM2CHRM1PABPC1BLMCYP2C19 | |
| Iodide SCHEMBL8509292 | 0.85 | PABPC1 (0.63) | CHRM2CHRM1PABPC1BLMCYP2C19 | |
| SCHEMBL8513388 | 0.83 | CTSS (0.44) | CHRM2CHRM1BLMCYP2C19CTSS | |
| Bromide SCHEMBL8509268 | 0.83 | CTSS (0.43) | CHRM2CHRM1BLMCYP2C19CTSS | |
| SCHEMBL17677464 | 0.80 | CHRNA7 (0.45) | CHRNA7CHRM2CHRM1BLMCTSS | |
| Phenactropinium SCHEMBL29387827 | 0.80 | CHRM2 (0.70) | CHRNA7CHRM2CHRM1PABPC1BLM | |
| Phenactropinium SCHEMBL8916468 | 0.80 | CHRM2 (0.70) | CHRNA7CHRM2CHRM1PABPC1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120134934-A1 | GLYCINE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120134934-A1 | GLYCINE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | CHRM3, GLRB, CHRNG | CHRNA7 48/4885CHRM2 4/4885CHRM1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.