SCHEMBL9290368

SCHEMBL9290368

COCCN1C(=O)c2cccc3cccc1c23

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
ALDH1A1 P00352 1/20 0.65
CASP1 P29466 1/20 0.65
MPI P34949 1/20 0.65
CACNA1B Q00975 1/20 0.65
APBA1 Q02410 1/20 0.65
POLB P06746 1/20 0.62
L3MBTL1 Q9Y468 2/20 0.55
KDM4E B2RXH2 1/20 0.55
CYP1B1 Q16678 1/20 0.53
UBE2N P61088 2/20 0.52
LMNA P02545 1/20 0.52
ATM Q13315 1/20 0.52
TDP1 Q9NUW8 2/20 0.52
HTR1A P08908 2/20 0.52
DRD2 P14416 2/20 0.52
HTR2A P28223 2/20 0.52
HTR7 P34969 2/20 0.52
HTR6 P50406 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6311318 0.89 HEXA (0.63) SMN1; SMN2ALDH1A1POLBKDM4ECYP1B1
Benzene SCHEMBL28662465 0.88 HEXA (0.61) HPGDSMN1; SMN2ALDH1A1POLBKDM4E
SCHEMBL11211234 0.85 HPGD (0.66) HPGDSMN1; SMN2ALDH1A1CASP1MPI
SCHEMBL12561280 0.83 ALDH1A1 (0.45) HPGDSMN1; SMN2ALDH1A1CASP1MPI
SCHEMBL9720971 0.82 HPGD (0.70) HPGDSMN1; SMN2ALDH1A1CASP1MPI
SCHEMBL9290301 0.82 ALDH1A1 (0.44) HPGDSMN1; SMN2ALDH1A1CASP1MPI
SCHEMBL22361783 0.81 HEXA (0.56) SMN1; SMN2ALDH1A1POLBKDM4ECYP1B1
SCHEMBL7131251 0.80 ALDH1A1 (0.71) HPGDSMN1; SMN2ALDH1A1CASP1MPI
SCHEMBL6275298 0.80 HEXA (0.65) HPGDSMN1; SMN2ALDH1A1POLBKDM4E
SCHEMBL7071975 0.80 ALDH1A1 (0.66) HPGDSMN1; SMN2ALDH1A1CASP1MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed
US-4332937-A DYES FOR POLYACRYLONITRILE CIBA-GEIGY CORPORATION (US) 1982-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152538-A1 OPTICAL FILTER C1R, CBR3, CBR1 HPGD 1268/4885SMN1; SMN2 2628/4885ALDH1A1 776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.