SCHEMBL6311318

SCHEMBL6311318

COCCN1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HEXA P06865 9/20 0.63
HEXB P07686 9/20 0.63
CYP1B1 Q16678 1/20 0.62
OGA O60502 1/20 0.61
NR1I2 O75469 1/20 0.59
POLB P06746 1/20 0.59
AHR P35869 1/20 0.59
RAD52 P43351 1/20 0.59
RCE1 Q9Y256 1/20 0.59
KDM4E B2RXH2 3/20 0.58
GAA P10253 2/20 0.58
ALDH1A1 P00352 1/20 0.58
MAPT P10636 1/20 0.58
RAB9A P51151 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
SIRT1 Q96EB6 2/20 0.56
CYP3A4 P08684 1/20 0.56
NFKB1 P19838 1/20 0.56
HSD17B10 Q99714 1/20 0.56
MEN1 O00255 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28662465 0.98 HEXA (0.61) HEXAHEXBCYP1B1OGANR1I2
SCHEMBL22361783 0.91 HEXA (0.56) HEXAHEXBCYP1B1OGANR1I2
SCHEMBL6275298 0.90 HEXA (0.65) HEXAHEXBCYP1B1OGANR1I2
SCHEMBL9290368 0.89 HPGD (0.65) CYP1B1POLBKDM4EALDH1A1SMN1; SMN2
SCHEMBL13885576 0.86 RXFP1 (0.52) HEXAHEXBCYP1B1OGAPOLB
SCHEMBL3642366 0.84 RAB9A (0.65) GAAALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL12243696 0.84 ALDH1A1 (0.59) KDM4EALDH1A1RAB9ASMN1; SMN2MEN1
SCHEMBL29530672 0.84 RAB9A (0.65) GAAALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL12660386 0.82 HEXA (0.62) HEXAHEXBCYP1B1OGANR1I2
SCHEMBL20258509 0.81 RXFP1 (0.58) HEXAHEXBNR1I2POLBAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11981626-B1 Compound embodiments for hydrogen sulfide production and methods of making and using the same UNIVERSITY OF OREGON (US) 2024-05-14 US claimed
US-11040942-B1 Compound embodiments for hydrogen sulfide production and methods of making and using the same UNIVERSITY OF OREGON (US) 2021-06-22 US claimed
US-10725055-B1 Compounds for carbonyl sulfide/carbon disulfide/hydrogen sulfide release and methods of making and using the same UNIVERSITY OF OREGON (US) 2020-07-28 US claimed
US-20240308939-A1 BI-FUNCTIONALIZED DICYCLOPENTADIENE MONOMER AND POLYMER EMBODIMENTS, AND METHODS OF MAKING AND USING SAME UVIC INDUSTRY PARTNERSHIPS INC. (CA) 2024-09-19 US disclosed
US-11981626-B1 Compound embodiments for hydrogen sulfide production and methods of making and using the same UNIVERSITY OF OREGON (US) 2024-05-14 US disclosed
US-11629128-B2 Compound and dimer complex embodiments for supramolecular sensing UVIC INDUSTRY PARTNERSHIPS INC. (CA) 2023-04-18 US disclosed
WO-2023285883-A1 BI-FUNCTIONALIZED DICYCLOPENTADIENE MONOMER AND POLYMER EMBODIMENTS, AND METHODS OF MAKING AND USING THE SAME UVIC INDUSTRY PARTNERSHIPS INC. (CA) 2023-01-19 WO disclosed
US-11078157-B1 Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same UNIVERSITY OF OREGON (US) 2021-08-03 US disclosed
US-20210214368-A1 COMPOUNDS FOR THIOL-TRIGGERED COS AND/OR H2S RELEASE AND METHODS OF MAKING AND USING THE SAME UNIVERSITY OF OREGON (US) 2021-07-15 US disclosed
US-11040942-B1 Compound embodiments for hydrogen sulfide production and methods of making and using the same UNIVERSITY OF OREGON (US) 2021-06-22 US disclosed
US-20200407318-A1 COMPOUND AND DIMER COMPLEX EMBODIMENTS FOR SUPRAMOLECULAR SENSING UVIC INDUSTRY PARTNERSHIPS INC. (CA) 2020-12-31 US disclosed
US-8211613-B2 prints, color filters, electronics, layer insulation films, wire covering films, optics, circuits, antireflection films, holograms and construction materials comprising a cured mixture of photosensitive resins and photoiniitiators having a naphthalimide structure DAI NIPPON PRINTING CO., LTD. (JP) 2012-07-03 US disclosed
US-8211613-B2 prints, color filters, electronics, layer insulation films, wire covering films, optics, circuits, antireflection films, holograms and construction materials comprising a cured mixture of photosensitive resins and photoiniitiators having a naphthalimide structure DAI NIPPON PRINTING CO., LTD. (JP) 2012-07-03 US disclosed
US-7528205-B2 Photo radical generator, photo sensitive resin composition and article DAI NIPPON PRINTING CO., LTD. (JP) 2009-05-05 US disclosed
US-7528205-B2 Photo radical generator, photo sensitive resin composition and article DAI NIPPON PRINTING CO., LTD. (JP) 2009-05-05 US disclosed
US-20080275154-A1 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition SAKAYORI KATSUYA 2008-11-06 US disclosed
US-20080275154-A1 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition SAKAYORI KATSUYA 2008-11-06 US disclosed
US-7410746-B2 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition DAI NIPPON PRINTING CO., LTD. (JP) 2008-08-12 US disclosed
US-7410746-B2 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition DAI NIPPON PRINTING CO., LTD. (JP) 2008-08-12 US disclosed
US-20050239833-A1 Compositions and methods for modulating interaction between polypeptides MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11040942-B1 Compound embodiments for hydrogen sulfide production and methods of making and using the same CBS, SQOR, SHMT2 HEXA 2421/4885HEXB 2419/4885CYP1B1 3058/4885
US-20050239833-A1 Compositions and methods for modulating interaction between polypeptides IAPP, SERPINA6, SERPINA2 HEXA 1620/4885HEXB 1556/4885CYP1B1 4838/4885
US-20210214368-A1 COMPOUNDS FOR THIOL-TRIGGERED COS AND/OR H2S RELEASE AND METHODS OF MAKING AND USING THE SAME CBS, TST, SQOR HEXA 3859/4885HEXB 3874/4885CYP1B1 4047/4885
US-11981626-B1 Compound embodiments for hydrogen sulfide production and methods of making and using the same CBS, SQOR, SHMT2 HEXA 2421/4885HEXB 2419/4885CYP1B1 3058/4885
US-11629128-B2 Compound and dimer complex embodiments for supramolecular sensing OPRM1, CNR2, CNR1 HEXA 3968/4885HEXB 4132/4885CYP1B1 1740/4885
US-11078157-B1 Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same CBS, SQOR, QSOX1 HEXA 1745/4885HEXB 2334/4885CYP1B1 2883/4885
US-20200407318-A1 COMPOUND AND DIMER COMPLEX EMBODIMENTS FOR SUPRAMOLECULAR SENSING OPRM1, CNR2, CNR1 HEXA 3968/4885HEXB 4132/4885CYP1B1 1740/4885
US-20240308939-A1 BI-FUNCTIONALIZED DICYCLOPENTADIENE MONOMER AND POLYMER EMBODIMENTS, AND METHODS OF MAKING AND USING SAME PUF60, MTHFD2, THEM6 HEXA 3430/4885HEXB 4113/4885CYP1B1 1497/4885
US-10725055-B1 Compounds for carbonyl sulfide/carbon disulfide/hydrogen sulfide release and methods of making and using the same CBS, SQOR, TST HEXA 3101/4885HEXB 2341/4885CYP1B1 2564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.