Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | APLNR | P35414 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3048494 | 0.90 | MAPK1 (0.71) | MAPK1GAAMAPTTSHRHTT | |
| SCHEMBL5612174 | 0.90 | APLNR (0.59) | MAPK1GAAMAPTTSHRHTT | |
| SCHEMBL16372548 | 0.88 | GAA (0.79) | MAPK1GAAMAPTTSHRHTT | |
| SCHEMBL31457262 | 0.88 | GAA (0.79) | MAPK1GAAMAPTTSHRHTT | |
| SCHEMBL19039711 | 0.86 | GAA (0.65) | MAPK1GAAMAPTTSHRHTT | |
| SCHEMBL9827146 | 0.85 | CYP19A1 (0.69) | MAPK1GAAMAPTTSHRHTT | |
| SCHEMBL15719428 | 0.83 | CYP19A1 (0.49) | MAPK1GAAMAPTTSHRHTT | |
| SCHEMBL5612171 | 0.83 | APLNR (0.53) | MAPK1GAAMAPTTSHRHTT | |
| SCHEMBL3300286 | 0.83 | LTA4H (0.58) | MAPTTSHRAPLNRALDH1A1 | |
| SCHEMBL15759453 | 0.82 | APLNR (0.51) | MAPK1GAAMAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364851-A | Internal coupling/cyclization to form helical structures | INTERNATIONAL SYNTHECON, LLC (US) | 1994-11-15 | — | — | US | disclosed |