Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27773350 | 0.79 | CACNA1B (0.50) | NPC1RAB9AALDH1A1GCGRKMT2A | |
| SCHEMBL29250490 | 0.78 | CACNA1B (0.46) | RAB9AALDH1A1GCGRKMT2AMTNR1A | |
| SCHEMBL931122 | 0.76 | NPC1 (0.60) | NPC1RAB9AALDH1A1KMT2ARECQL | |
| SCHEMBL383491 | 0.74 | RAB9A (0.51) | NPC1RAB9AALDH1A1GCGRKMT2A | |
| SCHEMBL5079813 | 0.74 | GPR52 (0.48) | NPC1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL6750240 | 0.73 | RAB9A (0.54) | NPC1RAB9AALDH1A1GCGRKMT2A | |
| SCHEMBL1303471 | 0.73 | NPC1 (0.85) | NPC1RAB9AALDH1A1KMT2ARECQL | |
| SCHEMBL10925556 | 0.72 | NR4A1 (0.48) | ALDH1A1KMT2AMAPTLMNAPTPN1 | |
| SCHEMBL7267678 | 0.71 | GPR52 (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2PTPN1 | |
| SCHEMBL16549911 | 0.71 | RAB9A (0.51) | NPC1RAB9AALDH1A1GCGRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359053-A | Nucleic acid probes having nucleoside residue; usable with stringent hybridization conditions | G. D. SEARLE & CO. (US) | 1994-10-25 | — | — | US | disclosed |
| US-5134066-A | Hybridization | MONSANTO COMPANY (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0415901-A2 | Improved nucleic acid probes | MONSANTO COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |