Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.68 |
| ▸ | CPB1 | P15086 | 1/20 | 0.65 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.65 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGAV | P06756 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14157482 | 0.90 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL18907028 | 0.90 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL18907025 | 0.90 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14157462 | 0.90 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14157463 | 0.90 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL464715 | 0.90 | FOLH1 (0.78) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL806151 | 0.90 | FOLH1 (0.78) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL4561005 | 0.90 | FOLH1 (0.78) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL7279464 | 0.89 | CTSK (0.55) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL18095595 | 0.89 | SYK (0.54) | FOLH1CPB1CPB2SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564561-A4 | PEPTIDES KETOAMIDES, KETOACIDS, AND KETOESTERS | GEORGIA TECH RES INST (US) | 1994-08-10 | — | — | EP | disclosed |
| EP-0564561-A1 | PEPTIDES KETOAMIDES, KETOACIDS, AND KETOESTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992012140-A1 | PEPTIDES KETOAMIDES, KETOACIDS, AND KETOESTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 1992-07-23 | — | — | WO | disclosed |