Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | CPB1 | P15086 | 1/20 | 0.52 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 6/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29576990 | 0.90 | ECE1 (0.63) | CTSKFOLH1SIRT2SIRT1ECE1 | |
| SCHEMBL7282552 | 0.89 | CTSK (0.51) | CTSKSIRT2SIRT1CTSLCTSS | |
| SCHEMBL5711357 | 0.89 | FOLH1 (0.60) | FOLH1TGM2SIRT2SIRT1ECE1 | |
| SCHEMBL5711236 | 0.89 | FOLH1 (0.60) | FOLH1TGM2SIRT2SIRT1ECE1 | |
| SCHEMBL9293333 | 0.89 | FOLH1 (0.68) | FOLH1TGM2SIRT2SIRT1CPB1 | |
| SCHEMBL29674796 | 0.88 | ECE1 (0.59) | CTSKFOLH1SIRT2SIRT1ECE1 | |
| SCHEMBL29372806 | 0.86 | MME (0.61) | CTSKFOLH1ECE1MMECAPN1 | |
| SCHEMBL9830575 | 0.84 | CAPN1 (0.62) | CTSKECE1MMECTSLCTSS | |
| SCHEMBL4558745 | 0.84 | CTSK (0.60) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL4561159 | 0.84 | CTSK (0.60) | CTSKCTSLCTSSCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518528-A | α Amino fluoro ketones | MP BIOMEDICALS, LLC | 1985-05-21 | — | — | US | disclosed |
| EP-0130679-A2 | Alpha amino fluoro ketones | ENZYME SYSTEMS PRODUCTS INC. (US) | 1985-01-09 | — | — | EP | disclosed |