Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NADK | O95544 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.33 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29328691 | 0.87 | ADORA2A (0.56) | ADORA2AADORA1ADORA3ADORA2BLMNA | |
| SCHEMBL29709122 | 0.87 | ADORA2A (0.56) | ADORA2AADORA1ADORA3ADORA2BLMNA | |
| SCHEMBL9495710 | 0.79 | ALDH1A1 (0.39) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL441053 | 0.79 | HIF1A (0.51) | ADORA2AADORA3LMNANADKPDE4D | |
| Didanosine SCHEMBL12150307 | 0.76 | ALDH1A1 (0.61) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL29387997 | 0.76 | ALDH1A1 (0.61) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL3364 | 0.76 | ALDH1A1 (0.61) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL1769151 | 0.76 | ALDH1A1 (0.61) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL8709115 | 0.75 | ALDH1A1 (0.60) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL7910803 | 0.75 | ALDH1A1 (0.60) | LMNAALDH1A1ALBMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549755-A4 | — | — | 1994-03-30 | — | — | EP | disclosed |
| EP-0549755-A1 | ddI IMMUNOASSAYS, DERIVATIVES, CONJUGATES AND ANTIBODIES | SIGMA CHEMICAL COMPANY (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5221611-A | DDI IMMUNOASSAYS, DERIVATIVES, CONJUGATES AND ANTIBODIES | SIGMA CHEMICAL COMPANY (US) | 1993-06-22 | — | — | US | disclosed |
| WO-1992022639-A1 | ddI IMMUNOASSAYS, DERIVATIVES, CONJUGATES AND ANTIBODIES | SIGMA CHEMICAL COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |