Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.56 |
| ▸ | NADK | O95544 | 2/20 | 0.51 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.46 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709122 | 1.00 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BADORA3NADK | |
| SCHEMBL9810618 | 0.88 | HSPA5 (0.57) | ADORA2AADORA1ADORA2BADORA3HSPA5 | |
| SCHEMBL9293816 | 0.87 | ADORA2A (0.40) | ADORA2AADORA1ADORA2BADORA3NADK | |
| SCHEMBL9617721 | 0.86 | HSPA5 (0.46) | ADORA2AADORA1ADORA2BADORA3HSPA5 | |
| SCHEMBL19680287 | 0.86 | AHCY (0.54) | ADORA2AADORA1ADORA2BADORA3HSPA5 | |
| SCHEMBL23679560 | 0.83 | HSPA8 (0.45) | ADORA2AADORA3HSPA5HSPA8LMNA | |
| SCHEMBL9810713 | 0.83 | HSPA8 (0.45) | ADORA2AADORA3HSPA5HSPA8LMNA | |
| SCHEMBL27767056 | 0.81 | LMNA (0.41) | ADORA2AADORA1ADORA2BADORA3NADK | |
| SCHEMBL14253676 | 0.79 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BADORA3NADK | |
| SCHEMBL659995 | 0.79 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BADORA3NADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854799-B1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | SHANGHAI DE NOVO PHARMATECH CO LTD (CN) | 2024-07-17 | — | — | EP | disclosed |