Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PLG | P00747 | 1/20 | 0.57 |
| ▸ | PLAT | P00750 | 1/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 5/20 | 0.43 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30484839 | 0.96 | LMNA (0.57) | LMNAPLGPLATANPEPCYP2D6 | |
| SCHEMBL5503267 | 0.96 | LMNA (0.57) | LMNAPLGPLATANPEPCYP2D6 | |
| SCHEMBL9504271 | 0.96 | LMNA (0.57) | LMNAPLGPLATANPEPCYP2D6 | |
| SCHEMBL3282964 | 0.96 | LMNA (0.57) | LMNAPLGPLATANPEPCYP2D6 | |
| SCHEMBL5503262 | 0.96 | LMNA (0.57) | LMNAPLGPLATANPEPCYP2D6 | |
| SCHEMBL9504278 | 0.96 | LMNA (0.57) | LMNAPLGPLATANPEPCYP2D6 | |
| SCHEMBL5722332 | 0.87 | LMNA (0.75) | LMNAPLGPLATANPEPCYP2D6 | |
| SCHEMBL4350693 | 0.87 | LMNA (0.75) | LMNAPLGPLATANPEPCYP2D6 | |
| SCHEMBL1965494 | 0.87 | LMNA (0.75) | LMNAPLGPLATANPEPCYP2D6 | |
| SCHEMBL28816390 | 0.87 | LMNA (0.75) | LMNAPLGPLATANPEPCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34722-E | Antiulcer agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| US-4578381-A | ANTIULCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-25 | — | — | US | disclosed |